Stadium: Wintrust Arena Round: 1
Home Manager: Brian Neal Away Manager: Doug Bruno
| WNCAAB | 2018/02/11 19:00 | Xavier (W) v DePaul (W) | L | 72-73 |
| WNCAAB | 2018/01/12 22:30 | Xavier (W) v DePaul (W) | L | 48-79 |
| WNCAAB | 2017/01/15 20:00 | Xavier (W) v DePaul (W) | L | 69-85 |
| WNCAAB | 2018/03/04 00:30 | Xavier (W) v Seton Hall (W) | L | 42-66 |
| WNCAAB | 2018/02/25 19:00 | Xavier (W) v Butler (W) | W | 57-54 |
| WNCAAB | 2018/02/18 18:00 | Providence (W) v Xavier (W) | L | 69-48 |
| WNCAAB | 2018/02/17 01:00 | Xavier (W) v Creighton (W) | L | 54-65 |
| WNCAAB | 2018/02/11 19:00 | Xavier (W) v DePaul (W) | L | 72-73 |
| WNCAAB | 2018/02/10 01:00 | Marquette (W) v Xavier (W) | L | 80-63 |
| WNCAAB | 2018/02/04 19:00 | Xavier (W) v St. John's (W) | L | 36-70 |
| WNCAAB | 2018/02/03 00:00 | Seton Hall (W) v Xavier (W) | L | 58-53 |
| Club Friendlies Women | 2018/08/19 18:00 | DePaul (W) v Adriatic Sea Sirens Women | W | 102-43 |
| WNCAAB | 2018/03/18 18:00 | Texas A&M (W) v DePaul (W) | L | 80-79 |
| WNCAAB | 2018/03/16 16:00 | DePaul (W) v Oklahoma (W) | W | 90-79 |
| WNCAAB | 2018/03/07 00:00 | DePaul (W) v Marquette (W) | W | 98-63 |
| WNCAAB | 2018/03/05 23:30 | Georgetown (W) v DePaul (W) | W | 53-85 |
| WNCAAB | 2018/03/05 00:00 | Seton Hall (W) v DePaul (W) | W | 52-78 |
| WNCAAB | 2018/02/25 18:00 | Seton Hall (W) v DePaul (W) | W | 68-72 |
| WNCAAB | 2018/02/24 00:00 | St. John's (W) v DePaul (W) | W | 54-67 |