[4] Tranmere 4-0 Scunthorpe [23] 2021-10-17 17:00
Stadium: Prenton Park Round: 26
Referee: Christopher Pollard Home Manager: Micky Mellon Away Manager: Keith John Hill
Head to Head
| England League 2 | 2021/08/28 14:00 | Scunthorpe v Tranmere | L | 1-0 |
| England League 2 | 2021/04/10 14:00 | Scunthorpe v Tranmere | D | 0-0 |
| England League 2 | 2020/10/03 14:00 | Tranmere v Scunthorpe | W | 2-0 |
Home History
| England League 2 | 2021/10/16 14:00 | Carlisle v Tranmere | W | 0-1 |
| England League 2 | 2021/10/08 18:45 | Tranmere v Colchester | W | 2-0 |
| England EFL Trophy | 2021/10/05 18:00 | Salford City v Tranmere | W | 0-2 |
| England League 2 | 2021/10/02 14:00 | Tranmere v Crawley Town | W | 2-1 |
| England League 2 | 2021/09/25 14:00 | Forest Green v Tranmere | D | 0-0 |
| England League 2 | 2021/09/18 14:00 | Tranmere v Salford City | W | 2-0 |
| England EFL Trophy | 2021/09/14 18:00 | Tranmere v Leeds U21 | W | 4-1 |
| England League 2 | 2021/09/11 14:00 | Rochdale v Tranmere | L | 1-0 |
Away History
| England League 2 | 2021/10/16 14:00 | Scunthorpe v Forest Green | L | 0-2 |
| England League 2 | 2021/10/09 14:00 | Harrogate Town v Scunthorpe | L | 6-1 |
| England EFL Trophy | 2021/10/05 18:00 | Rotherham v Scunthorpe | L | 4-1 |
| England League 2 | 2021/10/02 14:00 | Newport County v Scunthorpe | L | 3-0 |
| England League 2 | 2021/09/25 14:00 | Scunthorpe v Port Vale | L | 0-1 |
| England League 2 | 2021/09/18 14:00 | Carlisle v Scunthorpe | D | 2-2 |
| England League 2 | 2021/09/11 14:00 | Scunthorpe v Exeter | L | 0-4 |
| England League 2 | 2021/09/04 14:00 | Northampton v Scunthorpe | L | 2-0 |