[10] NY Islanders 2-1 NY Rangers [5] 2021-11-28 09:00
Stadium: Madison Square Garden
Home Manager: Barry Trotz Away Manager: Gerard Gallant
Head to Head
| NHL | 2021/11/25 00:30 | NY Rangers v NY Islanders | L | 4-1 |
| NHL Pre-Season | 2021/10/09 23:00 | NY Rangers v NY Islanders | L | 5-4 |
| NHL Pre-Season | 2021/09/26 23:00 | NY Islanders v NY Rangers | W | 4-0 |
| NHL | 2021/05/01 23:00 | NY Rangers v NY Islanders | W | 0-3 |
| NHL | 2021/04/29 23:00 | NY Islanders v NY Rangers | W | 4-0 |
| NHL | 2021/04/20 23:00 | NY Rangers v NY Islanders | W | 1-6 |
| NHL | 2021/04/11 23:00 | NY Rangers v NY Islanders | W | 2-3 |
| NHL | 2021/04/09 23:00 | NY Rangers v NY Islanders | L | 4-1 |
Home History
| NHL | 2021/11/27 00:30 | PIT Penguins v NY Islanders | L | 1-0 |
| NHL | 2021/11/25 00:30 | NY Rangers v NY Islanders | L | 4-1 |
| NHL | 2021/11/22 00:30 | TOR Maple Leafs v NY Islanders | L | 3-0 |
| NHL | 2021/11/21 00:00 | CGY Flames v NY Islanders | L | 5-2 |
| NHL | 2021/11/17 00:00 | NY Islanders v FLA Panthers | L | 1-6 |
| NHL | 2021/11/16 00:00 | NY Islanders v TB Lightning | L | 1-4 |
| NHL | 2021/11/12 00:00 | NY Islanders v NJ Devils | L | 0-4 |
| NHL | 2021/11/08 01:00 | NY Islanders v MIN Wild | L | 2-5 |
Away History
| NHL | 2021/11/26 18:00 | NY Rangers v BOS Bruins | W | 5-2 |
| NHL | 2021/11/25 00:30 | NY Rangers v NY Islanders | W | 4-1 |
| NHL | 2021/11/21 23:00 | BUF Sabres v NY Rangers | W | 4-5 |
| NHL | 2021/11/19 00:00 | NY Rangers v TOR Maple Leafs | L | 1-2 |
| NHL | 2021/11/17 00:00 | MTL Canadiens v NY Rangers | W | 2-3 |
| NHL | 2021/11/15 00:00 | NJ Devils v NY Rangers | W | 3-4 |
| NHL | 2021/11/14 00:00 | NY Rangers v CLB Blue Jackets | W | 5-3 |
| NHL | 2021/11/09 00:00 | FLA Panthers v NY Rangers | W | 3-4 |