| Uruguay Reserve League | 2018/03/17 17:00 | Defensor Sporting Reserves v Club Atletico Progreso Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/04/10 12:00 | Liverpool Montevideo Reserves v Club Atletico Progreso Reserves | L | 2-1 |
| Uruguay Reserve League | 2018/03/28 12:00 | Club Atletico Progreso Reserves v Racing Club de Montevideo Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/03/17 17:00 | Defensor Sporting Reserves v Club Atletico Progreso Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/03/13 13:00 | Club Atletico Progreso Reserves v CA Cerro Reserves | W | 1-0 |
| Uruguay Reserve League | 2018/03/07 13:00 | Club Atletico Progreso Reserves v Nacional de Montevideo Reserves | L | 0-4 |
| Uruguay Reserve League | 2018/02/21 13:00 | Club Atletico Progreso Reserves v Rampla Juniors Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/04/10 19:00 | Montevideo Wanderers Reserves v Defensor Sporting Reserves | W | 0-3 |
| Uruguay Reserve League | 2018/04/01 16:30 | Defensor Sporting Reserves v Atletico River Plate Reserves | L | 1-2 |
| Uruguay Reserve League | 2018/03/17 17:00 | Defensor Sporting Reserves v Club Atletico Progreso Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/03/13 13:00 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | D | 2-2 |
| Uruguay Reserve League | 2018/03/04 20:00 | Defensor Sporting Reserves v Atletico Fenix Reserves | L | 0-1 |
| Uruguay Reserve League | 2018/02/24 17:30 | Rampla Juniors Reserves v Defensor Sporting Reserves | W | 1-5 |
| Uruguay Reserve League | 2018/02/18 12:30 | Defensor Sporting Reserves v Torque Reserves | L | 2-4 |
| Uruguay Reserve League | 2018/02/04 20:00 | Defensor Sporting Reserves v Atenas Reserves | W | 4-2 |