Stadium: McGrath-Phillips Arena Round: 1
Home Manager: Joe Tartamella Away Manager: Doug Bruno
| WNCAAB | 2017/12/13 00:00 | Fordham (W) v St. John's (W) | L | 67-64 |
| WNCAAB | 2017/12/09 19:00 | St. John's (W) v James Madison (W) | W | 81-64 |
| WNCAAB | 2017/12/03 18:00 | St. John's (W) v Miami Florida (W) | W | 74-64 |
| WNCAAB | 2017/12/01 00:00 | Albany (W) v St. John's (W) | W | 66-71 |
| WNCAAB | 2017/11/26 22:00 | South Florida (W) v St. John's (W) | L | 68-59 |
| WNCAAB | 2017/11/25 22:00 | South Carolina (W) v St. John's (W) | L | 76-58 |
| WNCAAB | 2017/11/24 16:00 | Western Michigan (W) v St. John's (W) | W | 48-76 |
| WNCAAB | 2017/11/18 00:00 | St. John's (W) v William & Mary Women | W | 92-81 |
| WNCAAB | 2017/12/17 18:00 | DePaul (W) v Notre Dame (W) | L | 82-91 |
| WNCAAB | 2017/12/14 01:00 | DePaul (W) v Northwestern (W) | W | 92-63 |
| WNCAAB | 2017/12/09 00:00 | Connecticut (W) v DePaul (W) | L | 103-69 |
| WNCAAB | 2017/12/04 17:00 | Loyola Chicago (W) v DePaul (W) | W | 47-88 |
| WNCAAB | 2017/11/25 23:00 | Gonzaga (W) v DePaul (W) | W | 71-88 |
| WNCAAB | 2017/11/24 20:30 | Memphis (W) v DePaul (W) | W | 67-81 |
| WNCAAB | 2017/11/23 20:30 | DePaul (W) v Florida Gulf Coast (W) | L | 84-89 |
| WNCAAB | 2017/11/18 22:00 | St Louis Women v DePaul (W) | W | 78-86 |