Stadium: Moody Center Round: 122
Home Manager: Allison Pohlman Away Manager: Jeff Walz
| WNCAAB | 2022/11/27 16:00 | Howard Women v Drake (W) | W | 60-97 |
| WNCAAB | 2022/11/25 19:00 | Drake (W) v Massachusetts (W) | L | 83-100 |
| WNCAAB | 2022/11/19 20:00 | Nebraska (W) v Drake (W) | W | 62-80 |
| WNCAAB | 2022/11/13 20:00 | Iowa (W) v Drake (W) | L | 92-86 |
| WNCAAB | 2022/11/08 00:00 | Wisc Green Bay (W) v Drake (W) | W | 67-80 |
| NIT Women | 2022/03/25 00:00 | Drake (W) v South Dakota State (W) | L | 66-84 |
| NIT Women | 2022/03/21 23:00 | Northern Iowa (W) v Drake (W) | W | 55-62 |
| NIT Women | 2022/03/18 00:00 | Drake (W) v Missouri (W) | W | 83-78 |
| WNCAAB | 2022/11/25 17:00 | Longwood (W) v Louisville (W) | W | 37-100 |
| WNCAAB | 2022/11/21 22:00 | Louisville (W) v South Dakota State (W) | L | 55-65 |
| WNCAAB | 2022/11/21 00:30 | Texas (W) v Louisville (W) | W | 63-71 |
| WNCAAB | 2022/11/20 00:30 | Gonzaga (W) v Louisville (W) | L | 79-67 |
| WNCAAB | 2022/11/13 22:00 | Louisville (W) v Belmont (W) | W | 75-70 |
| WNCAAB | 2022/11/11 00:00 | IU Indianapolis Women v Louisville (W) | W | 62-84 |
| WNCAAB | 2022/11/07 22:00 | Cincinnati (W) v Louisville (W) | W | 68-87 |
| WNCAAB | 2022/04/01 23:00 | Louisville (W) v South Carolina (W) | L | 59-72 |