Stadium: Humphrey Coliseum Round: 1
Home Manager: Vic Schaefer Away Manager: Rekha Patterson
| WNCAAB | 2018/04/01 22:00 | Notre Dame (W) v Mississippi State (W) | L | 61-58 |
| WNCAAB | 2018/03/30 23:00 | Louisville (W) v Mississippi State (W) | W | 63-73 |
| WNCAAB | 2018/03/25 23:30 | UCLA (W) v Mississippi State (W) | W | 73-89 |
| WNCAAB | 2018/03/23 23:00 | NC State (W) v Mississippi State (W) | W | 57-71 |
| WNCAAB | 2018/03/20 01:00 | Oklahoma State (W) v Mississippi State (W) | W | 56-71 |
| WNCAAB | 2018/03/17 22:00 | Nicholls State (W) v Mississippi State (W) | W | 50-95 |
| WNCAAB | 2018/03/04 21:30 | South Carolina (W) v Mississippi State (W) | L | 62-51 |
| WNCAAB | 2018/03/03 22:00 | Mississippi State (W) v Texas A&M (W) | W | 70-55 |
| WNCAAB | 2018/02/28 21:00 | SE Missouri State (W) v Tennessee Martin (W) | L | 60-63 |
| WNCAAB | 2018/02/24 20:00 | SE Missouri State (W) v Tennessee Martin (W) | L | 68-69 |
| WNCAAB | 2018/02/22 22:30 | Eastern Kentucky (W) v SE Missouri State (W) | W | 52-66 |
| WNCAAB | 2018/02/17 20:00 | SE Missouri State (W) v SIU Edwardsville (W) | W | 72-62 |
| WNCAAB | 2018/02/15 00:30 | SE Missouri State (W) v Eastern Illinois (W) | W | 51-48 |
| WNCAAB | 2018/02/10 22:00 | Tennessee Martin (W) v SE Missouri State (W) | L | 72-65 |
| WNCAAB | 2018/02/08 22:15 | Morehead State (W) v SE Missouri State (W) | L | 60-58 |
| WNCAAB | 2018/02/03 20:00 | SE Missouri State (W) v Austin Peay Women | L | 50-61 |