| Mexico U21 League | 02/20 15:00 | 7 | [10] Puebla U21 v Club America U21 [4] | L | 4-5 | |
| Mexico U21 League | 02/13 15:00 | 6 | [7] Puebla U21 v Unam Pumas U21 [13] | D | 2-2 | |
| Mexico U21 League | 02/06 23:45 | 5 | [14] Tijuana U21 v Puebla U21 [11] | W | 1-2 | |
| Mexico U21 League | 01/30 15:00 | 4 | [10] Puebla U21 v Toluca U21 [3] | D | 1-1 | |
| Mexico U21 League | 01/17 15:00 | 3 | [18] Cruz Azul U21 v Puebla U21 [15] | W | 1-2 | |
| Mexico U21 League | 01/13 15:00 | 2 | [12] Puebla U21 v Christian Alvin Edison [10] | D | 0-0 | |
| Mexico U21 League | 01/09 15:00 | 1 | Atlas U21 v Puebla U21 | L | 5-2 | |
| Mexico U21 League | 11/08 15:00 | 17 | [7] Leon U21 v Puebla U21 [12] | W | 1-2 | |
| Mexico U21 League | 10/31 15:00 | 16 | [12] Puebla U21 v Cruz Azul U21 [4] | L | 0-1 | |
| Mexico U21 League | 10/24 15:00 | 15 | [14] Juarez FC U21 v Puebla U21 [9] | L | 1-0 | |
| Mexico U21 League | 10/21 15:00 | 14 | [10] Club America U21 v Puebla U21 [9] | D | 2-2 | |
| Mexico U21 League | 10/17 15:00 | 13 | [7] Puebla U21 v Tijuana U21 [5] | D | 1-1 | |
| Mexico U21 League | 10/04 15:00 | 12 | [18] Queretaro U21 v Puebla U21 [4] | L | 2-0 | |
| Mexico U21 League | 09/26 15:00 | 11 | [4] Puebla U21 v Ore/Smith [12] | D | 1-1 | |
| Mexico U21 League | 09/23 15:00 | 10 | [4] Puebla U21 v Pachuca U21 [1] | L | 0-4 | |
| Mexico U21 League | 09/19 15:00 | 9 | [3] Necaxa U21 v Puebla U21 [6] | W | 0-1 | |
| Mexico U21 League | 09/13 15:00 | 8 | [7] Toluca U21 v Puebla U21 [5] | D | 0-0 | |
| Mexico U21 League | 08/29 15:00 | 7 | Puebla U21 v Monterrey U21 | W | 6-4 | |
| Mexico U21 League | 08/24 15:00 | 6 | [8] Unam Pumas U21 v Puebla U21 [11] | W | 1-2 | |
| Mexico U21 League | 08/15 15:00 | 5 | [13] Puebla U21 v Atletico San Luis U21 [7] | W | 2-0 | |
| Mexico U21 League | 08/08 15:00 | 4 | [10] Tigres UANL U21 v Puebla U21 [8] | L | 1-0 | |
| Mexico U21 League | 07/25 15:00 | 3 | Puebla U21 v Santos Laguna U21 | W | 1-0 | |
| Mexico U21 League | 07/18 16:00 | 2 | Mazatlan FC U21 v Puebla U21 | L | 2-0 | |
| Mexico U21 League | 07/11 15:00 | 1 | Puebla U21 v Atlas U21 | D | 0-0 |