Head to Head
| XFL | 2024/09/10 10:06 | BUF Bills v CHI Bears | D | 0-0 |
| NFL Preseason | 2024/08/10 17:00 | CHI Bears v BUF Bills | L | 33-6 |
| NFL Preseason | 2023/08/26 17:00 | BUF Bills v CHI Bears | W | 24-21 |
| NFL | 2022/12/24 18:00 | BUF Bills v CHI Bears | W | 35-13 |
| NFL Preseason | 2021/08/21 17:00 | BUF Bills v CHI Bears | W | 41-15 |
| NFL | 2018/11/04 18:00 | CHI Bears v BUF Bills | L | 41-9 |
| NFL Preseason | 2018/08/31 00:00 | BUF Bills v CHI Bears | W | 28-27 |
| NFL | 2014/09/07 17:00 | CHI Bears v BUF Bills | W | 20-23 |
Home History
| NFL | 2025/01/26 23:30 | BUF Bills v KC Chiefs | L | 29-32 |
| NFL | 2025/01/19 23:30 | BAL Ravens v BUF Bills | W | 25-27 |
| NFL | 2025/01/12 18:00 | DEN Broncos v BUF Bills | W | 7-31 |
| NFL | 2025/01/05 18:00 | BUF Bills v NE Patriots | L | 16-23 |
| NFL | 2024/12/29 18:00 | NY Jets v BUF Bills | W | 14-40 |
| NFL | 2024/12/22 21:25 | NE Patriots v BUF Bills | W | 21-24 |
| NFL | 2024/12/15 21:25 | BUF Bills v DET Lions | W | 48-42 |
| NFL | 2024/12/08 21:25 | BUF Bills v LA Rams | L | 42-44 |
Away History
| NFL | 2025/01/05 18:00 | CHI Bears v GB Packers | W | 24-22 |
| NFL | 2024/12/27 01:15 | SEA Seahawks v CHI Bears | L | 6-3 |
| NFL | 2024/12/22 18:00 | DET Lions v CHI Bears | L | 34-17 |
| NFL | 2024/12/17 01:00 | CHI Bears v MIN Vikings | L | 12-30 |
| NFL | 2024/12/08 21:25 | CHI Bears v SF 49ers | L | 13-38 |
| NFL | 2024/11/28 17:30 | CHI Bears v DET Lions | L | 20-23 |
| NFL | 2024/11/24 18:00 | MIN Vikings v CHI Bears | L | 30-27 |
| NFL | 2024/11/17 18:00 | GB Packers v CHI Bears | L | 20-19 |